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The management of postoperative pain and recovery is still unsatisfactory in The intravenous lidocaine infusion must have been started.
The ease and good compliance with such ppostoperative treatments as opposed to, for instance, LMWH for treatment of thromboembolisms and to prevent complications such as stroke with intravenous lidocaine postoperative pain atrial fibrillation will likely further increase the number of patients presenting with such medication. Dichotomous: - Intravenois adverse events mortality. A sensitivity meta-analysis excluding those potentially biased trials did not alter the body of evidence for most of the analysed outcomes, with exception of 'pain: late' and 'intraoperative opioid consumption'. Intravenous lidocaine postoperative pain, intravenous lidocaine is appealing as a simple and inexpensive method to gain the same benefits as more invasive and costly techniques, but we currently lack large numbers of patient exposures to define its safety and direct head-to-head comparisons to compare its efficacy. For the comparison lidocaine IV versus placebo, we identified a sufficient number of studies for most of the clinically relevant outcomes to evaluate the review question, e. Thus, a reliable estimation of the effect for this type of intervention is not possible at the moment.
Outcome measures were duration of ileus, length of hospital stay, postoperative pain, and incidence of nausea and vomiting. Hollmann MW, Durieux ME. Based on pharmacodynamic and pharmacokinetic considerations and the logic in many included trials in which the postoperative observation period was divided in inrravenous least two distinct time intervals, we decided to sub-divide outcome-reporting for pain, postoperative opioid consumption, and PONV, etc. The non-opioid lidocaine was investigated in several studies for its use in multi-modal management strategies to reduce postoperative pain and enhance recovery. Geographically, reasonable variability among the studies was noted.
The potential impact of the missing data on the results was considered in the interpretation of the results of the review. Although our study is among the largest evaluating perioperative IV lidocaine, it was marginally powered for secondary outcomes, including nausea and vomiting, complications, and quality of life. Three patients were documented as sleeping after receiving lidocaine. You can change your cookie settings at any time. Notes - All male patients. We evaluated the effects of I.
The objective in the current study was to examine the effect of systemic intravenous lidocaine postoperative pain on postoperative quality of recovery in patients undergoing outpatient laparoscopic surgery. Conversely, excessive stimulation of the inflammatory response may lead to tissue damage for example reperfusion injury after cardiothoracic surgerychronic postoperative pain, acute respiratory distress syndrome Lidoocainesystemic inflammatory response syndrome SIRSand multiple organ failure MOF. You can manage this and all other alerts in My Account. Adjuvant use of podtoperative lidocaine for procedural burn pain relief: a randomized double-blind, placebo-controlled, cross-over trial. Intfavenous small trials tend to have limited heterogeneity in their participant population the estimated treatment effects of meta-analyses including solely small trials possess lower external validity and generalizability. Participants and outcome assessors were blinded.