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Lidocaine cerebral protection

lidocaine cerebral protection

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J Cardiothorac Vasc Anesth. 1999 Effect of lidocaine on improving cerebral protection provided by retrograde cerebral perfusion: a.
Lidocaine injected IV has been shown in models to induce cerebral .. and R. Chacornac, “ Lidocaine protection of the pressure of cerebral.

The importance of brain temperature in cerebral ischemic injury. However, there are currently no safe and efficacious agents available to protect the brain from ischemia. There exists evidence to both support and refute this. Advances in resuscitation science encourage progress in clinical manage- ment of these problems. Munir BoodhwaniFraser RubensDenise WoznyRosendo Rodriguez cereral, Howard J Lidocaine cerebral protection. Second, there exists evidence, though limited, to suggest an ICP reduction effect of IV lidocaine lidocxine used as a therapeutic measure.

lidocaine cerebral protection

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Peng L, Xu L, Ouyang W. Alternatively, benefit may be more likely for open-chamber surgery patients exposed to larger numbers of emboli or with a longer lidocaine infusion. Newman, Lee A Fleisher, Mitchell P. Effects of acadesine on the incidence of myocardial infarction and adverse cardiac outcomes after coronary artery bypass graft surgery. Cerebral perfusion in dogs during pulsatile and non-pulsatile extracorporeal circulation. The Wechsler Adult Intelligence Scale WAIS : WAIS is a test designed to assess the intelligence of adults and older adolescents. The likely mechanisms involved in the potential neuroprotective effects include slight increase of intracellular calcium, slight increase in CBF, upregulation of bioenergy metabolism, synthesis of nitric oxide and antiapoptotic factors, reduction of oxidative stress, and increased mitochondrial ATP-sensitive K channel activity.

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Mild intraoperative hypothermia during surgery for intracranial aneurysm. Compared with the preoperative MMSE scores, those on three days after surgery were significantly decreased in the control group. Furthermore, surgical procedures and cardio- determine whether it should be equally considered in thispulmonary bypass lidoaine were markedly different lidocaine cerebral protection of potential neuroprotective med4us.bidn the two trials. Other than the use of mild hypothermia for ventricular fibrillation cardiac arrest, practice of clinical neuroprotection rests. Neurocognitive dysfunction following cardiac surgery. This suggests that lidocaine suppresses the release of MDA.

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We performed a systematic review to determine the effectiveness of treatment with lidocaine in preventing the occurrence of cognitive deficit after cardiac surgery. Nitric oxide synthase NOS catalyzes the formation. Thus, a large-scale prospective human trial was conducted, but disappointing results were obtained. The review question and search strategy were decided upon by the primary author F. This study demonstrated that LBA exerted neuroprotective effects on cortical neurons exposed to homocysteine. Thiopental , a potent cerebrovasoconstrictor,. Atheroembolism from the ascending aorta: An emerging problem in cardiac surgery.

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